The POLish Bifurcation Optimal treatment Strategy study for Left Main bifurcation PCI (POLBOS) trial, is a prospective, multicenter, single-arm study in patients with an indication for distal unprotected left main revascularization (either isolated distal left main disease or associated with disease in other coronary arteries).
The treatment strategy consists of contemporary PCI of the left-main bifurcation following diagnostic angiography demonstrating significant distal unprotected left main disease and local Heart Team discussion applying the anatomic SYNTAX Score.
The presence of a significant lesion (%DS≥50) in any of the left main bifurcation segments (i.e., distal left main, ostial LAD or ostial LCX) must be confirmed by a central lab using dedicated bifurcation QCA. Pre-procedure iFR is mandatory to explore the physiological importance of the left main bifurcation.
IVUS preprocedure may be performed up to discretion of the investigator. IVUS assessment post-stent implantation for optimization of BiOSS LIM C deployment is highly recommended. The patients will be followed through 12 months to assess the clinical status and major clinical events.Study website log-in